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MUT-2691 L-23 (pf18 derivative)
Datasheet
Catalog No: ALS-02550
Product Details
Subategory:
Mutants
Description:
L-23 is a Chlamydomonas mutant obtained by MNNG mutagenesis of pf-18 followed by cell sorting. It has totally lost binding of a monoclonal antibody to an N-linked carbohydrate epitope on FMG-1B, exhibits normal binding of a monoclonal antibody to a protein epitope on FMG-1B and exhibits greatly increased binding of concanavalin A. This suggests a glycosylation mutant that results in a high mannose form (instead of the normal complex carbohydrate form) at the many glycosylation sites on FMG-1B (the major flagellar membrane glycoprotein) as well on other glycoproteins.
Species:
Chlamydomonas
Locus:
PF18, FMG1
Chromosome:
2,9
Phenotype:
Impaired motility
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For Research Use Only. Not For Clinical Use.