Transcriptomics Analysis Service of Algae
The transcriptome is the collection of all RNA transcripts in an individual or cell population. The study of the transcriptome enables the quantification of the expression level of each transcript as it changes during development and under different conditions.
As a comprehensive and integrated CRO company, Lifeasible can provide professional services to help clients analyze changes in the transcriptome under different conditions.
Introduction to RNA and Transcriptome
Organisms adapt to their immediate environment by altering the rate at which they synthesize proteins. This adaptation occurs primarily by regulating the expression of genes, the products of which enable the cell to survive in a given environment. The central law of genetics suggests that genetic information is transmitted from DNA to proteins via messenger RNA (mRNA) under sophisticated regulation. The expression profile of all genes, as well as their transcript levels, taken together, is called the transcriptome.
Transcriptomics analysis can be performed by DNA-Chip and transcriptome sequencing (RNA-Seq), which refers to cDNA sequencing using second-generation high-throughput sequencing technology to obtain comprehensive and rapid access to almost all transcripts of a particular organ or tissue of a species in a given state.
Fig.1 Pattern diagram of the central law.
The Differences between Genome and Transcriptomics Analysis
Compared to gene microarrays, transcriptomics analysis can detect the overall transcriptional activity of any species at any stage of development under specific conditions, providing more accurate digital signals, higher throughput, and a wider detection range. This makes it a powerful and superior technology for the in-depth study of complex transcriptomics changes.
The Importance of Transcriptomics Analysis
The purpose of whole transcriptomics analysis is to capture coding and non-coding RNAs and to quantify gene expression heterogeneity in cells, tissues, organs, and even the entire body. This analysis is important because it provides the first step in the functional characterization and annotation of genes or genomes previously revealed by DNA sequencing, and it studies gene function as well as gene structure at a global level to reveal specific biological processes and their molecular mechanisms.
Our Services
The algal transcriptome is often used at the molecular level to study the effects of changes in the survival environment on growth and physiology, to study microbial interactions and community ecology, to explore the molecular mechanisms of algal trophic strategies, and to study the potential of an organism to produce biofuels.
As a specialized algal research and analysis company, Lifeasible has extensive experience in transcriptomics sequencing and data analysis that supports the professional transcriptomics analysis services of algae.
Diverse Technologies
Hybridization-based technologies, such as cDNA microarrays and oligonucleotide acid microarrays, and sequencing-based technologies, such as multiple NGS (next-generation sequencing) platforms, are available.
Professional Data Analysis
Data analysis is a critical step in transcriptomics research. We have a professional team to perform high-quality assessments, sequence alignments, and differential expression analysis on raw data.
Why Choose Us
Lifeasible has been focusing on next-generation sequencing and transcriptomics analysis for many years and has accumulated a wealth of experience. Consequently, we are capable to provide high-quality transcriptomics analysis services for algae for our clients with experienced scientists and professional equipment. Please contact us for more information.
Our services are for research use only and not for any clinical use.