Fish Gene Editing

Gene editing (gene editing) refers to precise manipulation techniques such as site-directed insertion/deletion mutations, knockouts, simultaneous multi-site mutations, and small fragment deletions of genes at the genome level. Research on gene editing technology can help humans explore the essence of life, uncover the mystery of disease occurrence, and seek effective ways of disease prevention and treatment. The initial technical means of gene editing is gene targeting (gene targeting) mediated by homologous recombination. Although this technology can accurately modify specific genes, it has problems such as low efficiency, time-consuming, and possible gene mutation in actual operations. Which has affected the practical application of this technology.

In recent years, gene editing technology has developed vigorously, including zinc finger endonucleases (ZFN), transcription activator-like effector nucleases (TALEN), and regular clusters. Efficient gene editing tools such as clustered regularly interspaced short palindromic repeats (CRISPRs). Among them, CRISPR technology is currently one of the most widely used gene editing technologies.

The ocean is a treasure house of resources that humans continue to explore. Many economic species in the ocean, such as fish, shrimp, shellfish, and algae, are delicacies on the human table. However, with the increasing problems of overfishing and marine environmental pollution, the number of marine lives continues to decrease. The task of protecting marine organisms is imminent, and gene editing technology has shown broad application prospects in the fields of fish gene function research, animal disease prevention and breed improvement, and genetic disease gene therapy. At present, this type of technology has made important breakthroughs in many model fishes, such as successfully cultivating a new strain of yellow catfish with fast growth, high meat quality and large specifications, as well as many fish species with excellent characteristics.

Lifeasible has been deeply involved in the field of fish gene editing for many years, and has accumulated a wealth of theoretical and practical experience. We can help customers perform gene editing on different fish species:

Lifeasible has been in the field of gene editing for many years and has rich experience in gene editing of crops, ornamental plants, forest trees, fish, edible fungi and other species. The one-stop service we provide can provide a powerful boost to the scientific research process of our customers. For more information, please contact Lifeasible.