Exosomes are a type of extracellular vesicles, small membrane vesicles of endocytic origin secreted in cells with a lipid bilayer structure, widely present in various body fluids and cell culture supernatants, and carry active substances such as proteins, lipids, metabolites, and multiple nucleic acids. Large-scale polyomics analysis of exosomes can help in marker discovery, clinical diagnosis, and disease mechanism research.
Advantages of Exosome
- The ability of exosomes to act as biomarkers relies on the fact that they are rich in specific selective markers and that these markers represent only a tiny fraction of the secreted material. Thus, exosomes can detect low abundance nucleic acid or protein biomarkers that are difficult to detect with existing assays, and their biomarker strategy truly demonstrates that "less is more”.
- The lipid bilayer of exosomes protects their contents from nuclease and protease activity, and the extraction of exosomes from body fluids is performed non-invasive, making them an ideal alternative tool for early non-biopsy cancer detection.
- Exosomes are present in many parts of the organism, are easily accessible, and their amount reflects the rate of cellular metabolism in tissues. Analysis of their carriage can provide direct information on disease progression, recovery, and drug response.
Our Services
Lifeasible offers both exosome extraction and identification services, and exosome polyomics analysis, including proteomics, RNA analysis, lipidomics, and metabolites, all of which require high technical standards to ensure high-quality and reliable results. We are committed to providing high-quality services to support and facilitate the research users in all aspects of exosome polyomics research.
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Exosome Proteomics |
- Quantitative statistics of differential results, volcano plot, cluster heat map.
- Subcellular localization, structural domain analysis, GO functional analysis, KEGG enrichment analysis, interaction network and module analysis, WGCNA phenotype, and polyomics association analysis.
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| Exosome RNA Analysis |
- We have launched a system solution for exosomal RNA research, which will assist researchers in sequencing exosomal mRNA, miRNA, lncRNA, and circRNA services.
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| Exosome Lipidomics |
- Identification quantity and composition analysis: number of lipid subclasses and molecules identified, lipid subclass content ratio, and the dynamic distribution range of lipid content.
- Lipid content variation analysis: Total, Class level, Species level.
- Lipid chain length variation analysis, lipid chain saturation variation analysis.
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| Exosome Metabolomics |
- We provide efficient and accurate plant exosome metabolomics analysis services, especially primary and secondary metabolism analysis. We customize our services to meet your specific research needs, ensuring the highest precision comprehensive analysis services.
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| Exosome Whole Transcriptome Sequencing Services |
- The whole transcriptome sequencing service system fully combines micro nucleic acid library construction technology, NGS technology and novel bioinformation sequence matching algorithm to comprehensively capture and sequence mrnas, lncRNAs and circRNAs from exosomes, and realize the stable detection of a variety of long-chain RNAs.
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Technical process
Lifeasible offers the above services in addition to other services for exosomes, and our expertise can help you solve the problems you encounter with your project. If you are interested in our services, or if you want a service that is not listed, please feel free to contact us, and we will get back to you as soon as possible.
Our products/services are For Research Use Only. Not For Clinical Use!
