Analysis of Compounding Mechanisms of Herbal Medicines

Inquiry

Herbal compounding is the main form of clinical application of herbal medicine. The herbal medicine itself has many components, and the combination of components is even more complex, and the interrelationship between drugs is also very complicated. The elucidation of the mechanisms of action of herbal compound components and their combinations has become a difficult area of research, and appropriate research methods are a powerful tool for studying herbal compound combinations. Lifeasible uses modern high-sensitive, and high-resolution analytical techniques for the identification and analysis of chemical components and their contents and integrates various pharmacological methods for the analysis of the pharmacodynamic effects and interrelationships of the components of herbal compounding to help you study the combination pattern of herbal compounding and elucidate the multi-targeting mechanism of regulation of herbal compounding.

Analysis of compounding mechanisms of herbal medicines

Mechanism of compounding herbal medicines based on the analysis of potent substances

Pharmacodynamic substances are chemical substances that exert their medicinal effects in treating diseases in herbal compounding. We investigate the mechanism of compounding by examining whether new substances are produced, the content of active ingredients and toxic ingredients, etc., after compounding.

Analysis of the chemical composition of herbal medicines
Analysis of blood-borne components
Pharmacokinetic analysis

Research methods and strategies for the compounding mechanism of herbal medicines - Lifeasible

Analysis of herbal compounding mechanism based on signaling pathway index detection

Differences in the efficacy of herbs before and after compounding may be due to differences in the signaling pathways through which different herbs act. Our analysis of the expression of key enzymes, proteins, and genes in the relevant pathways can elucidate the compounding mechanism.

Metabolomics-based analysis of herbal compounding mechanisms

Metabolomics is a rapidly evolving field of systems biology that focuses on endogenous metabolite changes in response to external stimuli based on the overall metabolite profile of a biological sample. We can analyze potential biomarkers and metabolic pathways based on metabolomics, which can reflect the metabolic situation in the organism and reveal pathological and pharmacological intervention mechanisms, and its holistic and integrative character is more conducive to revealing complex herbal medicine pairing intervention mechanisms.

In addition, Lifeasible also uses differential proteomic and RNA-seq technologies to detect changes in protein expression levels and RNA expression to reflect changes in relevant signaling pathways or molecular markers after compounding, which can elucidate the compounding mechanisms of herbal medicines at the molecular level. Please feel free to contact us to elucidate the mechanism of herbal compounding through the study of changes in chemical composition, differences in blood-borne components, changes in pharmacokinetic parameters, similarities and differences in metabolites and metabolic pathways, and the number of drug target groups and pathway responses before and after compounding.

For Research Use Only. Not For Clinical Use.