Analysis of Medicinal Excipients for Herbal Medicines

Analysis of Medicinal Excipients for Herbal Medicines

Inquiry

Medicinal excipients are the basic materials and essential components of herbal preparations. It gives the drug a certain dosage form and has a great relationship with improving the efficacy and reducing the adverse effects of herbal medicines. The quality of medicinal excipients has an important impact on the safety and efficacy of the preparations. As an important component of herbal medicines, the safety of medicinal excipients cannot be ignored. To ensure that you are the first to know about the safety of medicinal excipients, Lifeasible offers analytical services for the separation and testing of solvents, co-solvents, emulsifiers, defoamers, diluents, protein protectors, and other herbal medicinal excipients.

Analysis of medicinal excipients for herbal medicines

Separation assays

The detection of pharmaceutical excipients often requires the separation of complex samples, and isocratic elution is not sufficient for the separation of most pharmaceutical excipients. The refractive index detector (RI) can detect compounds with weak or no UV absorption. We also offer an evaporative light scattering detector (ELSD) to compensate for the lack of RI, and can be used for gradient elution with significantly improved sensitivity. The ELSD performs particularly well in the detection of difficult, volatile compounds. In addition to the ELSD, the UV-Vis detector is highly sensitive. It has a wide linear range, which can be used to some extent for the quantitative analysis of pharmaceutical excipients.

Technical advantages

  • Can be used in conjunction with other detection techniques for more comprehensive analysis, ensuring that all components in the sample are detected.
  • Precise temperature control of the atomization, evaporation, and detection phases improves separation while maintaining low diffusivity and providing reproducible results.
  • Transmission of a signal to the LC system to stop the flow rate when low air pressure is detected.

Applications

  • Determination of the purity of the pharmaceutical excipient mannitol
  • Analysis of palmitic acid for pharmaceutical excipients
  • Simultaneous analysis of multiple fatty acids
  • Determination of TAG and DAG in triglyceride pharmaceutical excipients
  • Determination of phospholipids in pharmaceutical excipient oils
  • Determination of sucralose in pharmaceutical excipients
  • Determination of sodium ions in dantrolene sodium
  • Simultaneous determination of anions and cations in pharmaceutical intermediates
  • Analysis of sodium p-toluenesulfonate and hydrochloride in pharmaceuticals
  • Determination of dextran and poloxamer F68 in injectable solutions
  • Quantitative analysis of Tween 80 and polypropylene glycol in biological preparations
  • Quantitative determination of Tween 20 in high-concentration protein preparations, quantitative determination of histidine, arginine, sucrose, and mannitol in protein preparations

In addition to their role as excipients, carriers, and stability enhancers, pharmaceutical excipients have essential functions such as solubilization, solubilization aid, and slow and controlled release. They are important ingredients that may affect the quality, safety, and efficacy of herbal preparations. Lifeasible is committed to developing more and better methods for the testing of pharmaceutical excipients to make your work and research easier; please feel free to contact us for information.

For research or industrial raw materials, not for personal medical use!
Lifeasible provides high-level herbal medicine analysis services to facilitate related research. We also provide customers with a large number of high-quality products.
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