Evaluation of the Efficacy of Herbal Medicines

Inquiry

Validity evaluation is an essential prerequisite for discovering the material basis of herbal medicine efficacy, lead compounds, and quality markers. Lifeasible integrates herbal serum medicinal chemistry theory with metabolomics technology to establish a biological evaluation system for the efficacy of prescriptions based on the resolution of evidence-based biomarkers, which can help you to discover and identify the material basis of herbal efficacy.

We use metabolomics technology to discover and identify biomarkers, which are used as parameters to evaluate the effectiveness of prescriptions. In the active state, we use herbal serum medicinal chemistry to identify the active components of the formula entering the body, correlate them with the biomarker trajectory regression, and explore the components of the formula entering the body that are highly correlated with changes in the biomarker trajectory, thus identifying the pharmacodynamic basis of the clinical efficacy of the formula and elucidating its mechanism of action. This can help you solve effectiveness problems such as innovative drug design, quality marker discovery, and prescription formulation patterns.

Metabolomics techniques

We introduced metabolomics to establish new research methods to bridge the gap between herbal serum and medicinal chemistry in addressing effect evaluation. Metabolomics is an essential component of systems biology that can facilitate the resolution of the nature of disease and the complex mechanism of action of herbal remedies by considering the changes in the chemical composition of herbal remedies in vivo, in response to the complexity and holistic nature of their effects.

We use metabolomics techniques to obtain metabolic fingerprints and metabolic networks that reflect the functional state of the body through non-discriminatory analysis of endogenous small molecule metabolites. Metabolomics technologies can characterize evidence biomarkers, elucidate the biological nature of evidence, and provide data to support disease diagnosis and the establishment of relevant animal models. We have used metabolic profiles, metabolic fingerprints, and biomarkers to establish a biological evaluation system for the effectiveness of herbal medicines.

Herbal serum medicinal chemistry

Herbal serum medicinal chemistry is used primarily to analyze the substance base of herbal medicines. We offer an effective method for identifying metabolic fractions in blood using liquid chromatography and tandem mass spectrometry (LC-MS-MS), which provides comprehensive information on direct-acting substances. In addition to this, mass defect filtration (MDF) technology is also used to extract homologous fractions. It analyses mass spectral data by setting appropriate mass ranges and multiple filtering parameters, thereby filtering out many endogenous interferences.

Herbal serum medicinal chemistry - Lifeasible

Advantages

We use a reverse research strategy to uncover the material basis of efficacy. Based on the efficacy of a formula, we can evaluate the overall efficacy of a disease treatment, analyze the mechanism of action of the efficacy, analyze the effector components, and correlate the dynamic changes in the in vivo components and evidence biomarkers, with the associated components further biologically validated to determine the substance basis of the efficacy. We integrate disease elements, clinical chemistry, and metabolic markers of disease to evaluate the efficacy of formulations.

Lifeasible's approach can help you evaluate the efficacy of relevant formulations. Please feel free to contact us for information on the discovery of the substance bases and quality markers of herbal medicine.

For Research Use Only. Not For Clinical Use.