Preparation of Herbal Chemical Standards

Inquiry

Pharmaceutical standards are substances or materials used for physical, chemical, and biological testing in pharmaceutical standards, with defined characteristic values, for calibrating equipment, evaluating measurement methods or assigning values, or identifying drugs for testing. Pharmaceutical standards, like other standards, are characterized by the stability, uniformity, and accuracy of their values. Herbal chemical control is a physical control for studying herbal quality standards, quality testing, and quality control, and is used as a reference substance in drug testing and research. Lifeasible can provide you with the preparation and calibration of herbal chemical controls for determining the authenticity of herbal medicines and evaluating the quality of medications, helping you to improve the quality control of herbal medicines and ensure the safety and efficacy of medicines.

Preparation

Herbal medicine belongs to the category of natural chemicals, with many components and complex structures, making separating and purifying active ingredients difficult. Traditional separation techniques such as ultra-centrifugation, precipitation, extraction, and ultrafiltration often fail to achieve the required purity. We, therefore, use chromatographic separation techniques as a means of fine separation of such substances.

Herbal chemical controls for identification. It can be used for the qualitative analysis of herbal materials and preparations by thin-layer chromatography, gas chromatography, and liquid chromatography.
Herbal chemical controls for content determination. It can be used to determine the content of herbal materials, herbal monomeric components and analogs, herbal preparations, for qualitative examination by chromatography, UV spectrophotometry, colorimetric method, etc.
Chemical control for impurity check. It is used for the limited check of impurities in herbal active ingredient preparations.

Advantages of preparing herbal chemical controls - Lifeasible

Calibration

Herbal chemical controls are single components or mixed components used as standards for testing and can be classified as either for identification or for content determination. Before they have been calibrated, herbal chemical controls are called candidate controls.

Determine the variety of candidate controls. Generally, active ingredients, characteristic ingredients, or indicator ingredients are selected.
Development of the candidate control.

Calibration of herbal chemical controls - Lifeasible

After the preparation of the controls, calibration is the key.

For structural confirmation, we use various spectroscopic techniques to obtain various types of data and carry out detailed structural analysis and inference.
For purity checks, which require a purity of 95% or more for identification and 98% or more for content determination, we usually carry out tests using chromatography and perform methodological validation.
Assignments are made by the principles of the mass balance method, while those for identification do not require assignment as they do not involve the use of quantitative values. Assignments for content determination are made for chromatographic or spectroscopic purposes and according to the different use methods.
Stability tests are carried out to determine packaging and storage conditions and expiry dates.

Lifeasible has established technical methods for herbal chemical controls and their quality control. We help you to develop herbal chemical controls and standards by developing complete and rigorous analytical methods with scientifically detailed criteria. Please feel free to contact us to start your project and ensure that the quality of your herbs is under control.

For research or industrial raw materials, not for personal medical use!