Saussurea involucrata

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Saussurea involucrata contains flavonoids, alkaloids, lactone sterols, polysaccharides volatile oils, and other chemical components, and has a long history of folk medicinal use. Modern pharmacological studies have also shown that Saussurea involucrata has anti-inflammatory, anti-tumor, anti-early pregnancy, anti-aging, anti-fatigue, and free radical scavenging effects. To better develop and utilize this plant resource, Lifeasible can provide services such as extraction and detection of chemical and pharmacologically active ingredients, the establishment of an efficient plant regeneration system, preparation of flexible nano-liposomes, solid lipid nanoparticles (SLNs), and quality analysis of Saussurea involucrata.

What We Offer

Extraction and determination of total flavonoids and flavonoids

For the extraction of total flavonoids in Saussurea involucrata, we will use different methods according to the characteristics of the samples you provide, including solvent extraction, microwave extraction, ultrasonic extraction, ambient leaching method, heating reflux extraction method, and so on. To determine total flavonoids in Saussurea involucrata, we offer solvent flotation - UV spectrophotometry, etc.

We can compare the differences in the expression of active ingredients, structural genes, and transcription factors in different cell lines of Saussurea involucrata by using reversed-phase high-performance liquid chromatography (RPHPLC-DAD) and fluorescence real-time quantitative methods. This will help you to comprehensively analyze the relationship between gene expression and metabolites of the flavonoid synthesis pathway and further enhance your understanding of the molecular mechanism of secondary metabolism of flavonoids in Saussurea involucrata.

Establishment of an efficient plant regeneration system

Saussurea involucrata reproduces by seeds in the natural state, with a low germination rate and a long natural growth period. We can provide a solution to establish an efficient plant regeneration system for Saussurea involucrata based on tissue culture technology. Not only can we help you realize the rapid propagation of Saussurea involucrata, but we can also help develop the artificial cultivation of Saussurea involucrata to reduce the pressure on the extraction of wild resources. We also have experience in the induction of tetraploid Saussurea involucrata and can help you achieve different research objectives.

Preparation of flexible nanoliposomes based on Saussurea involucrata

Flexible nanoliposomes are a kind of self-aggregating vesicles prepared from liposomes by adding surface-active substances to phospholipid components. With high deformability, high hydrophilicity, and permeability, it is a new type of transdermal drug carrier with a better transdermal effect than liposomes. We can provide you with flexible nanoliposomes based on Saussurea involucrata and measure the particle size of the transporter, zeta potential, polydispersity index (PDI) value, drug loading, and encapsulation rate to evaluate the quality of flexible nanoliposomes, to ensure that we can provide you with high-quality finished products.

Preparation of Saussurea involucrata SLNs

SLNs have a high encapsulation rate, and low or almost non-toxicity, which can effectively improve the bioavailability of drugs, and at the same time can improve the stability of unstable drugs, and good lipid solubility makes them have slow controlled release and targeting effects. We offer you the preparation of Saussurea involucrata SLNs based on the high-pressure homogenization method and can characterize their particle size, potential, and encapsulation rate accordingly.

Quality analysis

We provide quality analysis strategies based on trait identification, microscopic identification, thin layer chromatography identification, and HPLC for determining moisture, total ash, acid insoluble ash, leachate, chlorogenic acid, and rutin in Saussurea involucrata. We also provide ICP-MS for determining heavy metal elements in Saussurea involucrata and RP-HPLC for determining dehydrocostus lactone in Saussurea involucrata. With the advantages of sensitivity, accuracy, and reproducibility, it can be more comprehensively used for the quality control and evaluation of Saussurea involucrata herbs.

Saussurea involucrata has a wide range of complex pharmacological activities. With so many varieties of snowdrops, there are still a large number of varieties of snowdrops waiting to be explored by researchers. Lifeasible can help you analyze and research different varieties of Saussurea involucrata and different tissue parts of Saussurea involucrata. Please feel free to contact us for more information.

For Research Use Only. Not For Clinical Use.