The Coleoptera are the most diverse and widespread first order of the insect family and indeed of the animal kingdom. It has a large number of species and a complex system. The forewings of this group are keratinised, rigid and veinless, and are called sheathwings, hence the name. There are four suborders (Protosauropoda, Mycophagidae, Carnivora and Polyphagidae), 178 families and 330,000 species, belonging to the winged subclasses, Allomorpha. Common insects (common names) include aspen, ladybird, glowworm, shittlebug, spotted worm, unicorn, giddyworm, parsnip, golden tortoise, stag beetle, knockworm, dragon louse, rice weevil.
As an important quarantine pest in forestry, the larvae of monochamus alternatus are the main damaging insect form and can be seen throughout the year. The larvae disrupt the transport of water and nutrients and cause the death of wood. Tribolium castaneum mainly affects flour, causing it to develop a musty smell and its secretions contain the carcinogen benzoquinone. Gene editing to control this pest is currently a hot topic. Lifeasible provides gene editing services for Coleoptera including monochamus alternatus-to control the harm caused by them and tribolium castaneum-to perform functional analysis of differentially expressed genes during the growth and development of tribolium castaneum and the development of insecticide resistance through sophisticated gene editing technology.
Species | Detail |
Monochamus alternatus |
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Tribolium castaneum |
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Leptinotarsa decemlineata |
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Harmonia axyridis | We could obtain Harmonia axyridis mutants with different phenotypes by knockout dopa decarboxylase (DDC), lac2, scarlet, and nAChRα6 using CRISPR/Cas9. |
We use zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALEN) and CRISPR/Cas9 to control monochamus alternatus, and piggyBac-mediated gene manipulation, RNA interference, and CRISPR/Cas9-mediated gene editing to help customers study the tribolium castaneum biology and search for new insecticide targets of tribolium castaneum.
We can use several methods to edit variety of genes in monochamus alternatus to affect the development of monochamus alternatus. We can also edit some specific genes in tribolium castaneum according to your needs by three means to control this organism.
Lifeasible provides gene editing services for Coleoptera including monochamus alternatus and tribolium castaneum to study the specific functions in the growth and development of these organisms and find the new insecticide targets in monochamus alternatus and tribolium castaneum to control them through sophisticated gene editing technology. If you are interested in our services or if you have any questions, please click online inquiry for more detailed information.