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Gene Editing in Hymenoptera

Gene Editing in Hymenoptera

Hymenoptera is a large order of insects, comprising the sawflies, wasps, bees, and ants. Over 150,000 living species of Hymenoptera have been described, in addition to over 2,000 extinct ones. Many of the species are parasitic. Females typically have a special ovipositor for inserting eggs into hosts or places that are otherwise inaccessible. This ovipositor is often modified into a stinger. The young develop through holometabolism (complete metamorphosis)-that is, they have a wormlike larval stage and an inactive pupal stage before they mature. Different species of Hymenoptera show a wide range of feeding habits. The most primitive forms are typically phytophagous, feeding on flowers, pollen, foliage, or stems. Stinging wasps are predators, and will provision their larvae with immobilised prey, while bees feed on nectar and pollen.

Our Services for Gene Editing in Hymenoptera

Pheidole megacephala belong to the order Hymenoptera, the ant family. Ants are diverse, long-lived and typically social groups. Gene editing in ants is not yet well established, and published articles are limited to reports of knocking out olfactory-related genes. Bees are social insects, consisting of individuals such as queens, males and worker bees. The technology for gene editing in bees is now relatively mature. Lifeasible provides service of gene editing in Hymenoptera including Gene Editing in Pheidole Megacephala-to manipulate the social behavior of this organism, and Gene Editing in Bee-to optimize the genetic traits of bee with CRISPR/Cas9.

Species Detail
Pheidole megacephala
  • Edit olfactory-related genes to reduce social interaction, affect sensory and olfactory cues in the ants' brains, and affect the function of ants' olfactory system.
Bee
  • Edit immune-related genes to interfere with the body's immune system, like immune response to pathogenic infection, and the response process of the body's immune system after pathogen infection.
  • Edit growth and development-related genes to affect all growth and development stages of bee.
  • Edit sex determination genes to affect larval sex development and maintenance, and even leads to embryonic death.
Harpegnathos saltator We offer genome editing of orco loci based on CRISPR/Cas9 technology can help you obtain loss-of-function mutations and propagate them through Harpegnathos saltator's germline.
Nasonia vitripennis We can perform RNA silencing by RNAi or gene knockout by CRISPR/Cas9 genome editing, which will allow you to functionally analyze genes of interest in Nasonia vitripennis to study a wide range of biologically essential phenomena in this organism.

Our Methods for Gene Editing in Hymenoptera

  • CRISPR/Cas9

Lifeasible provides gene editing services for pheidole megacephala and bee through the system of CRISPR/Cas9. The genes encoding the Cas9 protein and sgRNA are introduced into a cell to alter the target gene as planned according to your needs.

Advantages

  • Editing olfactory-related genes to affect the function of pheidole megacephala' olfactory system.
  • Editing the genes involved in sex determination, growth and development-related genes, and immune response-related genes to affect all growth and development stages of bee.

Lifeasible provides service of gene editing in Hymenoptera including Gene Editing in Pheidole Megacephala, and Gene Editing in Bee by CRISPR/Cas9 to affect the olfactory system, and interfere the social behavior of pheidole megacephala, and affect the immune system, and other growth and development stages of bee. If you are interested in our services or if you have any questions, please click online inquiry for more detailed information.

Our Services are for Research Use Only. Not for Clinical Use!
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