Product Name
Cytochalasin E
Description
Cytochalasin E, an epoxide containing Aspergillus-derived fungal metabolite, inhibits angiogenesis and tumor growth. Cytochalasin E is a potent actin depolymerization agent, and it binds and caps the barbed end of actin filaments to prevent actin elongation.
Structural Formula
Cytochalasin E
Source
the fungus R. necatrix
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
O=C1[C@]2(O3)[C@]([C@@H]([C@](O4)(C)[C@@H]4[C@]2([H])/C=C/C[C@@H](C([C@](C)(O)/C=C/OC3=O)=O)C)C)([H])[C@H](CC5=CC=CC=C5)N1
In Vitro
Cytochalasin E prominently inhibits the growth of A549 cells in a dose-dependent manner.Cytochalasin E could induce the up-regulation of autophagy-related protein (LC3-II) and SQSTM1/p62.
Datasheet 
