Cytochalasin E
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Cytochalasin E

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Cat#
ALK-0315
Product Name
Cytochalasin E
CAS No.
36011-19-5
Description
Cytochalasin E, an epoxide containing Aspergillus-derived fungal metabolite, inhibits angiogenesis and tumor growth. Cytochalasin E is a potent actin depolymerization agent, and it binds and caps the barbed end of actin filaments to prevent actin elongation.
Structural Formula
Cytochalasin E
MW
495.56
MF
C28H33NO7
Purity
0.999
Appearance
Solid
Source
the fungus R. necatrix
Storage
-20℃ for 3 years
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
O=C1[C@]2(O3)[C@]([C@@H]([C@](O4)(C)[C@@H]4[C@]2([H])/C=C/C[C@@H](C([C@](C)(O)/C=C/OC3=O)=O)C)C)([H])[C@H](CC5=CC=CC=C5)N1
In Vitro
Cytochalasin E prominently inhibits the growth of A549 cells in a dose-dependent manner.Cytochalasin E could induce the up-regulation of autophagy-related protein (LC3-II) and SQSTM1/p62.
 Datasheet  
For research or industrial raw materials, not for personal medical use!
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