Product Name
(+)-Intermedine
Description
(+)-Intermedine, a pyrrolizidine alkaloid (PA), exhibits significant cytotoxicity in neural progenitor cells (NPCs).
Structural Formula
(+)-Intermedine
Solubility
DMSO : 50 mg/mL
Source
Plants >Boraginaceae > Symphytum officinaleL.
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
CC(C)[C@@]([C@H](O)C)(O)C(OCC1=CCN2[C@@]1([H])[C@H](O)CC2)=O
In Vitro
(+)-Intermedine (1.1-30 μM; 24 hours) exhibits significant cytotoxicity at 30 μM and reduces cell viability in a concentration dependent manner in neural progenitor cells (NPCs). (+)-Intermedine showsno differentiation impairment.
Datasheet 
