Product Name
10Z-Hymenialdisine
Synonyms
(Z)-Hymenialdisine; Hymenialdisine
Description
10Z-Hymenialdisine ((Z)-Hymenialdisine) is a natural bioactive pyrrole alkaloid. 10Z-Hymenialdisine is a pan kinase inhibitor, and has anticancer activities.
Structural Formula
10Z-Hymenialdisine
Source
marine sponge Axinella carteri
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
O=C1C2=C(C=C(N2)Br)/C(CCN1)=C3C(N=C(N/3)N)=O
In Vitro
10Z-Hymenialdisine displays a moderate effect on (ARK5, VEGFR-2, SAK and PDGFR) protein kinases. 10Z-Hymenialdisine shows a potent inhibition of RAF/MEK-1/MAPK cascade with an IC50 value of 6 nM.
Datasheet 
