Retrorsine N-oxide

Retrorsine N-oxide

Cat#
ALK-0334
Product Name
Retrorsine N-oxide
CAS No.
15503-86-3
Description
Retrorsine N-oxide, an N-oxide of pyrrolizidine alkaloid, is a carcinogen. Retrorsine N-oxide-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides.
Structural Formula
Retrorsine N-oxide
MW
367.39
MF
C18H25NO7
Source
Plants >Leguminosae > Baptisia australis(L.) R. Br. >Plants >Compositae
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
O=C(/C(C[C@H]([C@@](O)(C(OCC1=CC2)=O)CO)C)=C\C)O[C@@]3([H])[C@]1([H])[N+]2([O-])CC3
In Vivo
Retrorsine N-oxide produces DNA adducts, the common biological biomarker of PA-induced liver tumor formation.
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