Product Name
(-)-Integerrimine
Description
(-)-Integerrimine, a pyrrolizidine alkaloid, has antiulcerogenic activity. (-)-Integerrimine is also a mutagenic and weakly clastogenic agent in Drosophila.
Structural Formula
(-)-Integerrimine
Source
Plants >other families
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
O=C1O[C@@]2([H])[C@]3([H])N(CC=C3COC([C@](O)([C@@H](C/C1=C\C)C)C)=O)CC2
In Vitro
(-)-Integerrimine (0.00625-0.05 mM) also must have mutagenic activity in somatic cells of Drosophila. (-)-Integerrimine in general requires cytochrome P450-dependent metabolic activation to exhibit genotoxic activity.