Product Name
Hippeastrine
Description
Hippeastrine, an active alkaloid, exhibits a good dose-dependent inhibitory effect against topoisomerase I (Top I) with an IC50 at 7.25 μg/mL. Antiproliferative and anticancer activities.
Structural Formula
Hippeastrine
Source
Plants >Amaryllidaceae > Narcissus tazettaLinn. var. chinensis M.Roener
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
O=C1O[C@]([H])([C@H](C=C2CCN(C32)C)O)[C@@]3([H])C4=CC5=C(OCO5)C=C14
In Vitro
Hippeastrine strongly inhibits the proliferation of HT-29 and Hep G2 cells in an intuitive dose-dependent manner with the IC50s at 3.98 μg/mL and 11.85 μg/mL, respectively, and also induces significant cellular morphological changes, which further validate our screening method and the potent antineoplastic effects.
Datasheet 
