Product Name
Vindesine sulfate
Description
Vindesine sulfate is a potent tubulin inhibitor with an Ki of 0.110 µM. Vindesine sulfate shows anti-proliferation effect in vitro. Vindesine sulfate shows antitumor effect in vivo.
Structural Formula
Vindesine sulfate
Solubility
DMSO : 250 mg/mL(293.43 mM;Need ultrasonic)
Source
Plants >Apocynaceae > Catharanthus roseus(L.) G. Don
Storage
4℃, sealed storage, away from moisture
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
O=S(O)(O)=O.CC[C@@]12[C@@]3([H])[C@@]4(CCN3CC=C2)C5=CC([C@@]6(C7=C(CC[N@]8C[C@@](C[C@](O)(C8)CC)([H])C6)C9=CC=CC=C9N7)C(OC)=O)=C(OC)C=C5N([C@@]4([H])[C@](O)([C@@H]1O)C(N)=O)C
In Vitro
Vindesine sulfate inhibits L-cells growth and shows about 25% inhibition at 40 nM.