Product Name
Hemiasterlin
Synonyms
(-)-Hemiasterlin; Milnamide B
Description
Hemiasterlin ((-)-Hemiasterlin) is an antimitotic marine natural product with potent anticancer effcts. Hemiasterlin can be used as a cytotoxic payload (ADC Cytotoxin) in antibody-drug conjugates (ADCs).
Structural Formula
Hemiasterlin
Storage
-20℃, protect from light
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
OC(/C(C)=C/[C@H](C(C)C)N(C)C([C@H](C(C)(C)C)NC([C@@H](NC)C(C)(C1=CN(C)C2=CC=CC=C12)C)=O)=O)=O
In Vitro
Hemiasterlin is an antimitotic agent by disrupting microtubule dynamics causing mitotic arrest and cell death with low- to sub-nanomolar potencies against several cancer cell lines.
Datasheet 
