Product Name
Geissoschizoline
Synonyms
(+)-Geissoschizoline
Description
Geissoschizoline ((+)-Geissoschizoline) is a potent inhibitor of human AChE/BChE, with IC50s of 20.40 µM and 10.21 µM, respectively. Geissoschizoline emerges as a possible multi-target prototype that can be very useful in studies of preventing neurodegeneration and restoring neurotransmission. Geissoschizoline aiso is a potent anti-inflammatory agent.
Structural Formula
Geissoschizoline
Source
Plants >Pteridaceae > Pteris wallichianaAgardh >Plants >other families
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
OC[C@@H]1[C@@]2([H])[C@]3(C4=CC=CC=C4N2)[C@@]5([H])N(C[C@H]([C@]1([H])C5)CC)CC3
In Vitro
Geissoschizoline(1 μM; 48 hours) significantly reduces production of TNF-α and NO in LPS-stimulated microglial cells.
Datasheet 
