Product Name
Shishijimicin A
Description
Shishijimicin A is a novel antitumor agent found from the Ascidian Didemnum proliferum. Shishijimicin A shows anti-tumor activity with highly potent cytotoxicities.
Structural Formula
Shishijimicin A
Source
Didemnum proliferum
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
O=C(C1=C(NC2=CC=C3O)C(C2=C3)=CC=N1)[C@@]([C@@H]([C@H]4O[C@H](OC[C@@H]5NC(C)C)C[C@@H]5OC)O)([C@H](O[C@H]4O[C@@H](C#C/C=C\C#C[C@@]6(C7)O)C(/C6=C\CSSSC)=C(C7=O)NC(OC)=O)C)SC
In Vitro
Shishijimicin A (compound 1) (0.47-2.0 pg/mL) shows high cytotoxicity for 3Y1, Hela and P388 cells.Shishijimicin A (0.13-1000 nM) shows high cytotoxicity for MES SA, MES SA DX and HEK 293T cells.
Datasheet 
