Product Name
Shishijimicin B
Description
Shishijimicin B is an active compound of the enediyne class. Shishijimicin B shows extremely potent cytotoxicity with IC50 values of 2.0-3.3 nM. Shishijimicin B has antitumor activity and can be used for the research of cancer.
Structural Formula
Shishijimicin B
Source
Didemnum proliferum
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
CSSSC/C=C([C@]1(C2)O)\C([C@H](C#C/C=C\C#C1)O[C@H](O[C@@H]3C)[C@@H]([C@H]([C@@H]3C(C4=C(NC5=CC=C6O)C(C5=C6)=CC=N4)=O)O)O[C@H](OC[C@@H]7NC(C)C)C[C@@H]7OC)=C(C2=O)NC(OC)=O
In Vitro
Shishijimicin B (compound 2) has high cytotoxicity for 3Y1, Hela and P388 cells with IC50 values of 3.1 nM, 3.3 nM and 2.0 nM, respectively.
Datasheet 
