Fumitremorgin B

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Cat#

ALK-0515

Product Name

Fumitremorgin B

CAS No.

12626-17-4

Description

Fumitremorgin B is a tremorgenic mycotoxin. Fumitremorgin B exhibits significant antifungal activities, with MICs of 6.25-50 μg/mL.

Structural Formula

Fumitremorgin B

479.57

C27H33N3O5

Source

fungus Aspergillus fumigatus

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere.

SMILES

O=C([C@]1(O)[C@@H](O)C2=C([C@H](/C=C(C)\C)N13)N(C/C=C(C)\C)C4=C2C=CC(OC)=C4)N5[C@](CCC5)([H])C3=O

In Vitro

Fumitremorgin B (3 or 4 days) inhibits the proliferation of U937 and PC3 cells, with IC50 of 14.12 and 43.36 μM, respectively. Fumitremorgin B exhibits antifungal activities against the phytopathogenic fungi B. cinerea, A. solani, A. alternata, C. gloeosporioides, F. solani, F. oxysporum f. sp. niveum, F. oxysporum f. sp. vasinfectum, and G. saubinettii, with MICs of 6.25-50 μg/mL.

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