Product Name
Vallesiachotamine
Description
Vallesiachotamine, a known monoterpene indole alkaloid, possesses anti-tumor activity.
Structural Formula
Vallesiachotamine
Source
Plants >Apocynaceae > Melodinus suaveolens(Hance) Champ. ex Benth.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
C/C=C([C@@H]1C[C@@]2([H])C3=C(CCN2C=C1C(OC)=O)C4=CC=CC=C4N3)/C=O
In Vitro
Vallesiachotamine induces G0/G1 arrest and increased the proportion of sub-G1 hypodiploid cells (at 11 μM and 22 μM) and this effect is not dependent on time of incubation. Vallesiachotamine acts by promoting G0/G1 cell cycle arrest, apoptosis and necrosis.