10-Hydroxycamptothecin

10-Hydroxycamptothecin

Cat#
ALK-0585
Product Name
10-Hydroxycamptothecin
CAS No.
19685-09-7
Description
(S)-10-Hydroxycamptothecin (10-HCPT;10-Hydroxycamptothecin) is a DNA topoisomerase I inhibitor of isolated from the Chinese plant Camptotheca accuminata. (S)-10-Hydroxycamptothecin exhibits a remarkable apoptosis-inducing effect. (S)-10-Hydroxycamptothecin has the potential for hepatoma, gastric carcinoma, colon cancer and leukaemia treatment.
MW
364.36
MF
C20H16N2O5
Purity
>98.0%
Appearance
White to Yellow to Orange powder to crystal
Melting Point
267°C
Condition to Avoid
Heat Sensitive
Physical State (20 deg.C)
Solid
Reaxys Registry Number
3019077
Specific rotation [a]20/D
35.3° (C=0.11,CH2Cl2:MeOH=4:1)
Signal Word
Danger
Hazard Statements
H301 H311 H331 : Toxic if swallowed, in contact with skin or if inhaled.
RTECS#
UQ0491700
UN Number (DOT-AIR)
UN1544
Class (DOT-AIR)
6.1
Packing Group
III
HS Number
2934.99.4400
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