Synonyms
Boldine chloroform; 4H-Dibenzo[de,g]quinoline-2,9-diol, 5,6,6a,7-tetrahydro-1,10-dimethoxy-6-methyl-; Boldin; 2,6-dihydroxy-3,5-dimethoxyaporphine; 5,6,6a,7-Tetrahydro-1,10-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-2,9-diol; 1,10-dimethoxy-2,9-dihydroxyaporphine; Uniboldina; 2,9-Dihydroxy-1,10-dimethoxyaporphine; 1,10-Dimethoxy-6aa-aporphine-2,9-diol; dl-Boldine; 1,10-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol
Description
Boldine is an aporphine isoquinoline alkaloid extracted from the root of Litsea cubeba and also possesses these properties, including antioxidant, anti-inflammatory and cytoprotective effects. Boldine suppresses osteoclastogenesis, improves bone destruction by down-regulating the OPG/RANKL/RANK signal pathway and may be a potential therapeutic agent for rheumatoid arthritis.
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