Product Name
(−)-Riboflavin
Product Overview
This product is suitable for cell culture. CAS NO.83-88-5.
Description
Riboflavin belongs to the vitamin-B family and contains a pentose side chain ribitol. Riboflavin is a key component of the redox cofactors flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) that are used by a wide variety of flavoprotein oxidoreductases, dehydrogenase(s), decarboxylase(s) and electron transporters. Riboflavin is involved in various cellular processes, including β oxidation in lipid metabolism, glucose metabolism, protection from cellular oxidative injury, DNA and RNA metabolism, gluconeogenesis, erythropoiesis and generation of corticosteroids. Riboflavin deficiency causes ariboflavinosis with symptoms such as sore throat, hyperemia, edema of oral and mucous membranes, cheilosis and glossitis.
Source
Eremothecium ashbyii
Applications
Riboflavin has been used:
• to check the role of riboflavin diet in rats
• as a supplement in HECM-6 medium (hamster embryo culture medium)
• as a supplement in the bacterial basal media
Stability
The flavins are light sensitive and unstable in alkaline solutions. The dry solid is stable to diffuse light, but is highly photolabile in solution, especially in alkaline solutions. Neutral and acidic solutions are stable in the dark (3% decomposition per month at 27 °C at
pH 6.0). Acidic solutions may be sterilized by autoclaving.
Storage
Store at Room Temperature
Reconstitution
Riboflavin is slightly soluble in water. One g dissolves in 3 - 15 L water, depending on the crystal structure. It is less soluble in alcohol than in water (4.5 mg in 100 ml of absolute ethanol at 27 °C). Riboflavin is very soluble in dilute alkalies, but is unstable. A 10 mg/ml solution in 0.1 M NaOH forms a clear, yellow to orange solution.
Synonyms
Lactoflavin; Vitamin B2; Vitamin G
Molecular Formula
C17H20N4O6
Datasheet 
