Product Name
Convallatoxin
Product Overview
The product belongs to plant extarct.
Source
Convallaria majalis
Form
White crystal powder
Solubility
Soluble in alcohol, acetone; Slightly soluble in water, chloroform; Insoluble in petroleum ether.
Applications
As cardiotonic, sedative and diuretic drugs
Synonyms
3β,5α,14-Trihydroxy-19-oxo-5β,20(22)-cardenolide 3-(6-deoxy-α-L-mannopyranoside) Strophanthidin α-L-rhamnopyranoside
Function
Convallatoxin is a cardiac glycoside isolated from Adonis amurensis Regel et Radde. Convallatoxin ameliorates colitic inflammation via activation of PPARγ and suppression of NF-κB. Convallatoxin is a P-glycoprotein (P-gp) substrate and recognized Val982 as an important amino acid involved in its transport. Convallatoxin is an enhancer of ligand-induced MOR endocytosis with high potency and efficacy. Anti-inflammatory and anti-proliferative properties.
Molecular Formula
C29H42O10
Datasheet 
