Vinblastine

EXT-2283

Vinblastine

The product belongs to plant extarct.

Catharanthus roseus (L.)G.Don

White crystal solid

810.99

Soluble in methanol, ethanol, DMSO and other organic solvents

Vincristine mainly inhibits the polymerization of microtubule proteins and prevents the formation of spindle microtubules, causing tumor cells to stop mitosis at mid-stage. Vincristine can also act on the cell membrane, interfering with the transport of amino acids by the cell membrane, causing inhibition of protein synthesis, and also inhibiting RNA synthesis.

Keep sealed at 2-8°C, dry and protected from light.

VincristineEPImpurityH; VINBLASTINESULFATE(RG); [3aR-[3aa,4b,5b,5ab,9(3R*,5S*,7R*,9S*),10bR*,13aa]]-Methyl4-(acetyloxy)-3a-ethyl-9-[5-ethyl-1,4,5,6,7,8,9,10-octahydro-5-hydroxy-9-(methoxycarbonyl)-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-3a,4,5,5a,6,11,12,13a-octahydro-5-hydroxy-8-methoxy-6-methyl-1H-indolizino[8,1-cd]carbazole-5-carboxylate; 1H-Indolizino[8,1-cd]carbazole,vincaleukoblaChemicalbookstinederiv.; 1H-Indolizino[8,1-cd]carbazole-5-carboxylicacid,4-(acetyloxy)-3a-ethyl-9-[5-ethyl-1,4,5,6,7,8,9,10-octahydro-5-hydroxy-9-(methoxycarbonyl)-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-3a,4,5,5a,6,11,12,13a-octahydro-5-hydroxy-8-methoxy-6-methyl-,methylester,[3aR-[3aa,4b,5b,5ab,9(3R*,5S*,7R*,9S*),10bR*,13aa]]-; 2H-3,7-Methanoazacycloundecino[5,4-b]indole,vincaleukoblastinederiv.

Vincristine acts on M-phase cells, mainly inhibiting the polymerization of microtubule proteins, thus affecting the formation of spindle microtubules in the cells and stopping the mitosis of tumor cells in M-phase. It also acts on the cell membrane, interfering with the operation of amino acids in the cell membrane and inhibiting the synthesis of proteins.

C46H58N4O9

212-734-0

865-21-4

2 years

0.99