Product Name
Quinolinic acid
Description
Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction.
Structural Formula
Quinolinic acid
Solubility
DMSO : 33.33 mg/mL(199.44 mM;Need ultrasonic) H2O : 3.33 mg/mL(19.93 mM;Need ultrasonic)
IC50 & Target
Topoisomerase I
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
O=C(C1=NC=CC=C1C(O)=O)O
In Vitro
Quinolinic acid (0-50 mM; 24 hours) decreases the percentage of survival cells ranging from 100±0.01% at 5 mM to 45.23±0.01% at 50 mM in N18D3 cells.