Description
Peimisine (Ebeiensine) is a muscarinic M receptor antagonist and angiotensin converting enzyme (ACE) inhibitor. Peimisine shows anti-tumor, anti-inflammatory, antihypertensive activities. Peimisine can induce apoptosis and be used in cough and asthma research.
Solubility
DMSO : 12.5 mg/mL(29.23 mM;ultrasonic and heat to 60°C)
Source
Plants >Liliaceae > Fritillaria cirrhosa
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
O=C1[C@](C[C@@H](O)CC2)([H])[C@@]2(C)[C@@]3([H])CC4=C(C)[C@@]5(O[C@@]6([H])[C@@]([C@H]5C)([H])NC[C@@H](C)C6)CC[C@@]4([H])[C@]3([H])C1
In Vitro
Peimisine (17.43-92.07 μg/mL; 72 h) shows significant cytotoxic effects.Peimisine (15 μg/mL; 24, 48 and 72 h) induces G0/G1 phase arrest and rising apoptosis rate.