Description
Bullatine A, a diterpenoid alkaloid of the genus Aconitum, possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects. Bullatine A is a potent P2X7 antagonist, inhibits ATP-induced cell death/apoptosis and P2X receptor-mediated inflammatory responses. Bullatine A attenuates pain hypersensitivity, regardless of the pain models employed.
Solubility
DMSO : 12.5 mg/mL(36.39 mM;ultrasonic and warming and heat to 80°C)
Source
Plants >Ranunculaceae > Aconitum carmichaeliDebx.
Storage
4℃, protect from light
IC50 & Target
D1 Receptor α1-adrenergic receptor
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
O[C@H](C1C2([C@@H]3O)C4C[C@]5([H])[C@@]6(C)CCCC51C4N(CC)C6)C(CC2)C3=C
Datasheet 
