Description
Evocarpine, a quinolone alkaloid that could be isolated from Evodiae fructus, inhibitss Ca2+ influx through voltage-dependent calcium channels. Antimycobacterial activity.
Structural Formula
Evocarpine
Solubility
DMSO : 100 mg/mL(294.54 mM;Need ultrasonic)
Source
Plants >Rutaceae > Evodia rutaecarpa(Juss.) Benth.
Storage
4℃, protect from light
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
O=C1C=C(CCCCCCC/C=C\CCCC)N(C)C2=C1C=CC=C2
In Vitro
Cumulative application of evocarpine (1-100 μM) inhibits the sustained contraction induced by 60 mM K+ in a concentration-dependent manner. Evocarpine is found to induce apoptotic cell death in promyelocytic leukaemia HL‐60 cells in dose- and time-dependent manners.
Datasheet 
