Deoxycytidine triphosphate

Deoxycytidine triphosphate

Cat#
ALK-0143
Product Name
Deoxycytidine triphosphate
CAS No.
2056-98-6
Synonyms
dCTP; 2′-Deoxycytidine-5′-triphosphate
Description
Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
Structural Formula
Deoxycytidine triphosphate
MW
467.16
MF
C9H16N3O13P3
Appearance
Solid
Solubility
H2O : 50 mg/mL(107.03 mM;Need ultrasonic)
Storage
-20℃ for 3 years
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
O[C@H]1C[C@H](N2C(N=C(C=C2)N)=O)O[C@@H]1COP(O)(OP(OP(O)(O)=O)(O)=O)=O
In Vitro
Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to growth inhibition by 1-β-D-arabinofuranosylcytosine (ara-C) revealed a spectrum between the most and least sensitive which differed 100-fold from each other. An inverse correlation between sensitivity and cellular Deoxycytidine triphosphate (2′-Deoxycytidine-5′-triphosphate, dCTP) content is found, and this suggested that sensitivity of cells might be increased if the dCTP content was lowered during cell exposure to ara-C.Deoxycytidine triphosphate trisodium salt is a phosphoethanolamine cytidylyltransferase substrate.
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