Nitidine chloride

Nitidine chloride

Cat#
ALK-0206
Product Name
Nitidine chloride
CAS No.
13063-04-2
Description
Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis, inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A, ERK and c-Src/FAK associated signaling pathway. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway.
Structural Formula
MW
383.82
MF
C21H18ClNO4
Purity
0.9961
Appearance
Solid
Solubility
DMSO : 2 mg/mL(5.21 mM;Need ultrasonic)
Source
Plants >Rutaceae > Zanthoxylum nitidum(Roxb.) DC.
Storage
4℃, sealed storage, away from moisture and light
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
C[N+]1=CC2=CC(OC)=C(OC)C=C2C(C=CC3=C4)=C1C3=CC5=C4OCO5.[Cl-]
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