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Groenlandicine

Groenlandicine

Cat#
ALK-0225
Product Name
Groenlandicine
CAS No.
38691-95-1
Description
Groenlandicine is a protoberberine alkaloid isolated from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR). Groenlandicine selectively induces topoisomerase I-mediated DNA cleavage.
Structural Formula
Groenlandicine
MW
322.33
MF
C19H16NO4+
Purity
0.9969
Appearance
Solid
Solubility
DMSO : 1 mg/mL(3.10 mM;ultrasonic and warming and heat to 60°C)
Source
Plants >Ranunculaceae > Coptis chinensisFranch.
Storage
4℃, protect from light
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
COC1=CC2=C(C=C1O)CC[N+]3=CC4=C(C=CC5=C4OCO5)C=C23
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