Phellodendrine chloride

Phellodendrine chloride

Cat#
ALK-0228
Product Name
Phellodendrine chloride
CAS No.
104112-82-5
Description
Phellodendrine chloride is a plant alkaloid found in Phellodendron amurense. Phellodendrine chloride suppresses the proliferation of KRAS mutated pancreatic cancer cells through inhibition of nutrients uptake via macropinocytosis . Phellodendrine chloride promotes autophagy by regulating the AMPK/mTOR pathway and reduce the intestinal damage of ulcerative colitis.
Structural Formula
MW
377.86
MF
C20H24ClNO4
Purity
0.9979
Appearance
Solid
Solubility
DMSO : 50 mg/mL(132.32 mM;Need ultrasonic)
Source
Plants >Rutaceae > Phellodendron amurenseRupr.
Storage
4℃, sealed storage, away from moisture and light
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
C[N@@+]12CCC3=CC(OC)=C(O)C=C3[C@]1([H])CC4=CC(O)=C(OC)C=C4C2.[Cl-]
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