8-Oxocoptisine

8-Oxocoptisine

Cat#
ALK-0234
Product Name
8-Oxocoptisine
CAS No.
19716-61-1
Description
8-Oxocoptisine is a natural protoberberine alkaloid with anti-cancer activity.
Structural Formula
8-Oxocoptisine
MW
335.31
MF
C19H13NO5
Purity
>99.0%
Appearance
Solid
Solubility
DMSO : 2.08 mg/mL(6.20 mM;ultrasonic and warming and heat to 60°C)
Source
Plants >Ranunculaceae > Coptis chinensisFranch.
Storage
-20℃ for 3 years
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
O=C1N2C(C3=CC(OCO4)=C4C=C3CC2)=CC5=CC=C6C(OCO6)=C15
In Vitro
8-Oxocoptisine has cytotoxicity against NCI-N87 (IC50=20.31 μM) and has no cytotoxicity against Caco-2 (IC50>100 μM).
For research or industrial raw materials, not for personal medical use!
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