Product Name
(+)-Coclaurine
Synonyms
(+)-(R)-Coclaurine; (R)-Coclaurine; d-Coclaurine
Description
(+)-Coclaurine ((+)-(R)-Coclaurine), benzyltetrahydroisoquinoline alkaloid isolated from a variety of plant sources. (+)-Coclaurine has anti-aging activity.
Structural Formula
(+)-Coclaurine
Solubility
DMSO : 25 mg/mL(87.61 mM;ultrasonic and warming and heat to 60°C)
Source
Plants >Lauraceae > Lindera aggregata(Sims) Kosterm.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
OC(C=C1)=CC=C1C[C@@H]2C3=CC(O)=C(OC)C=C3CCN2
In Vivo
An intracerebroventricular injection of (+)-Coclaurine (d-Coclaurine; 50 μg) produces a slight increase in 3,4-dihydroxyphenylacetic acid level and a significant increase in homovanillic acid level in the mouse striatum. (+)-Coclaurine blocks postsynaptic but not presynaptic dopamine receptors in the mouse striatum.
Datasheet 
