Product Name
Isochondrodendrine
Synonyms
Isochondrodendrin
Description
Isochondrodendrine ( Isochondrodendrin) is a class of bisbenzylisoquinoline alkaloid isolated from Isolona ghesquiereina. Isochondodendrine has strong antiplasmodial activity against Plasmodium falciparum.
Structural Formula
Isochondrodendrine
Source
Plants >Pteridaceae > Adiantum philippenseL. Sp. >Plants >other families
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
OC1=C(OC2=CC=C(C=C2)C3)C4=C(C=C1OC)CCN(C)[C@]4([H])CC(C=C5)=CC=C5OC6=C(O)C(OC)=CC7=C6[C@]3([H])N(C)CC7
In Vivo
Isochondrodendrine has strong in vitro antiplasmodial activity against the chloroquine resistant strain FMC29 of Plasmodium falciparum. Toxicity observed is 50 to 100 fold greater towards Plasmodium falciparum than cultured L6 cells.