Gene Editing Services in Candida

Candida is a genus of yeast which commonly causes fungal infections worldwide. Several species of Candida have been sequenced. And some of them are source of industrial lipases. For assisting global customers developing the applications of it, Lifeasible offers markerless gene editing services in Candida, with methods based on recombinases system.

Overview of Candida

Organisms of Candida are the most common cause of fungal infections. Many of them cause diseases only when mucosal barriers are disrupted or the immune system is compromised in the host. Among Candida, some of them are normal constituent of the human flora. While some of them increasingly cause infections because they are less susceptible to antifungals. And there are some species are used as biological control agents in fruit. Some of them have potential in producing single cell oil due to their naturally high lipid accumulation capacity.

Typical Strains of Candida

• Candida albicans
  C. albicans is an opportunistic pathogenic yeast, which is commonly used as a model organism of fungal pathogens. It causes deadly infections in immunocompromised individuals. C. albicans cells exist as diploid, haploid and tetraploid. And it has been used to combined with carbon nanotubes for producing stable electrically conductive bio-nano-composite tissue materials which is used as temperature-sensing elements.
• Candida krusei
  C. krusei is important in chocolate producing. And it's also an emerging pathogen, which is found in individuals with hematological malignancies. Mortality caused by C. krusei is much higher than C. albicans. Besides, it can be cultured in vitamin-free media.
• Industrial Enzymes
  C. antarctica and C. rugosa are source of industrial important lipases. They are widely used to catalyze the regioselective acylation of flavonoids or the direct acetylation with phenolic acids.

Our Services

Lifeasible provides gene editing services in Candida for assisting researchers studying mechanism of these pathogens and finding way to control them, and we expect to contribute in developing better applications of Candida for other purpose like industrial production and environment conservation. Our experienced scientists dedicate to provide trustable and satisfying services for our customers.

Gene Knock-out Services in Candida

• Markerless Single Gene Knock-out Services

In order to assist our global customers understanding the regulatory mechanism of reactions happen in Candida, Lifeasible provide site-specific gene knock-out services.

• Markerless Multiple Gene Knock-out Services

Lifeasible provides our customers multiple gene knockout services for studying gene-gene interaction and redundant gene function. Our scientists established a robust toolkit of multiple site-specific recombinases for implementing markerless multiple gene knock-out in Candida.

Gene Knock-in Services in Candida

We offer gene knock-in service in Candida for customers who need overexpressed or knocked-in yeast strains for further research.

Service Process

Advantages

Lifeasible offers our customers innovative, efficient, customer-tailored and high-quality gene editing services. And we promise to deliver the results and products on time and with high quality. We serve researchers all over the world with heart and soul. Please feel free to contact us.