Catalog Number: RNPP-74351027
| Size: 200µl 2ml Customization | Inquiry |
|---|
| Gene ID: | PP7435_Chr1-1096 |
| Gene Name: | ATG7 |
| Gene Location: | chr1: 1983609..1985573 |
| DNA Length (bp): | 1965 |
| Protein Length (aa): | 654 |
| Gene Description: |
Ubiquitin-like modifier-activating enzyme ATG7 (Autophagy-related protein 7) E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production |
| Medium: |
YPD + 1M Sorbitol broth 30% glycerol |
| Shipping condition: | Frozen Gel Packs |
| Storage condition/Stability: |
-80℃/At least 12 months 4°C/Up to 1 week |
| Hazardous: | No |
Disclaimer
This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.
