Products

Pichia pastoris CBS 7435 CGI121 Knockout Strain

Catalog Number: RNPP-74351613

Size: 200µl 2ml Customization Inquiry
Gene Information
Gene ID: PP7435_Chr1-3237
Gene Name: CGI121
Gene Location: chr1: 2650815..2651333
DNA Length (bp): 519
Protein Length (aa): 172
Gene Description: EKC/KEOPS complex subunit CGI121 (EKC/KEOPS complex subunit cgi121)
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37
CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex
The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation
The complex is required for efficient recruitment of transcriptional coactivators
CGI121 is not required for tRNA modification
Specifications
Medium: YPD + 1M Sorbitol broth
30% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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