Products

Pichia pastoris CBS 7435 DNA2 Knockout Strain

Catalog Number: RNPP-74354960

Size: 200µl 2ml Customization Inquiry
Gene Information
Gene ID: PP7435_Chr4-0722
Gene Name: DNA2
Gene Location: chr4: 1224462..1228703
DNA Length (bp): 4242
Protein Length (aa): 1413
Gene Description: DNA replication ATP-dependent helicase/nuclease (EC 3.1.-.-) (EC 3.6.4.12)
Key enzyme involved in DNA replication and DNA repair
Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1
Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA
Specifications
Medium: YPD + 1M Sorbitol broth
30% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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