Products

Pichia pastoris CBS 7435 MDM12 Knockout Strain

Catalog Number: RNPP-74353876

Size: 200µl 2ml Customization Inquiry
Gene Information
Gene ID: PP7435_Chr3-0959
Gene Name: MDM12
Gene Location: chr3: 1721367..1722233
DNA Length (bp): 867
Protein Length (aa): 288
Gene Description: Mitochondrial distribution and morphology protein 12 (Mitochondrial inheritance component MDM12)
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria
Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria
MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10
The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex
The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex
Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids
Specifications
Medium: YPD + 1M Sorbitol broth
30% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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