Products

Pichia pastoris CBS 7435 NCS6 Knockout Strain

Catalog Number: RNPP-74353374

Size: 200µl 2ml Customization Inquiry
Gene Information
Gene ID: PP7435_Chr3-0418
Gene Name: NCS6
Gene Location: chr3: 761241..762329
DNA Length (bp): 1089
Protein Length (aa): 362
Gene Description: Cytoplasmic tRNA 2-thiolation protein 1 (EC 2.7.7.-) (Cytoplasmic tRNA adenylyltransferase 1)
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln)
Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation
It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position
Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation
May also be involved in protein urmylation
Specifications
Medium: YPD + 1M Sorbitol broth
30% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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