Catalog Number: RNPP-74352440
| Size: 200µl 2ml Customization | Inquiry |
|---|
| Gene ID: | PP7435_Chr2-0857 |
| Gene Name: | PIF1 |
| Gene Location: | chr2: 1582033..1584417 |
| DNA Length (bp): | 2385 |
| Protein Length (aa): | 794 |
| Gene Description: |
ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs Involved in the maintenance of telomeric DNA Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase Reduces the processivity of telomerase by displacing active telomerase from DNA ends Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction Involved in the maintenance of ribosomal (rDNA) |
| Medium: |
YPD + 1M Sorbitol broth 30% glycerol |
| Shipping condition: | Frozen Gel Packs |
| Storage condition/Stability: |
-80℃/At least 12 months 4°C/Up to 1 week |
| Hazardous: | No |
Disclaimer
This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.
