Catalog Number: RNPP-74351345
| Size: 200µl 2ml Customization | Inquiry |
|---|
| Gene ID: | PP7435_Chr1-1444 |
| Gene Name: | RAD27 |
| Gene Location: | chr1: 2595515..2596636 |
| DNA Length (bp): | 1122 |
| Protein Length (aa): | 373 |
| Gene Description: |
Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (Flap structure-specific endonuclease 1) Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity Also involved in replication and repair of rDNA and in repairing mitochondrial DNA |
| Medium: |
YPD + 1M Sorbitol broth 30% glycerol |
| Shipping condition: | Frozen Gel Packs |
| Storage condition/Stability: |
-80℃/At least 12 months 4°C/Up to 1 week |
| Hazardous: | No |
Disclaimer
This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.
