Products

Pichia pastoris CBS 7435 RRM3 Knockout Strain

Catalog Number: RNPP-74352650

Size: 200µl 2ml Customization Inquiry
Gene Information
Gene ID: PP7435_Chr2-1077
Gene Name: RRM3
Gene Location: chr2: 1962269..1964344
DNA Length (bp): 2076
Protein Length (aa): 691
Gene Description: ATP-dependent DNA helicase RRM3 (EC 3.6.4.12) (rDNA recombination mutation protein 3)
5' to 3' DNA replicative helicase recruited to paused replisomes to promote fork progression throughout nonhistone protein-DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses
Required for timely replication of the telomere and subtelomeric DNA and for wild-type levels of telomeric silencing
Involved in DNA repair during stalled replication fork, regulation of fragile sites expression and essential for genome stability
Plays also a role in mtDNA replication
Has G-quadruplex (G4) unwinding activity and can suppress G4-induced genome instability when PIF1 levels are low
Specifications
Medium: YPD + 1M Sorbitol broth
30% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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