Products

Pichia pastoris CBS 7435 SUS1 Knockout Strain

Catalog Number: RNPP-74352110

Size: 200µl 2ml Customization Inquiry
Gene Information
Gene ID: PP7435_Chr2-0511
Gene Name: SUS1
Gene Location: chr2: 945075..945365
DNA Length (bp): 291
Protein Length (aa): 96
Gene Description: Transcription and mRNA export factor SUS1
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes
At the promoters, SAGA is required for recruitment of the basal transcription machinery
It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination
Within the SAGA complex, participates to a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels
The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket)
TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery
May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies
Specifications
Medium: YPD + 1M Sorbitol broth
30% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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